adenine-hcl

Description: Adenine HCl (6-Aminopurine; Vitamin B4; NSC 14666; NSC-14666), the hydrochloride salt of adenine, is a purine analog and an adenine receptor agonist with a Ki of 18 nM at rat adenine receptors. It is one of the 4 chemical bases (nucleobases) in DNA (represented by the letters G–C–A–T, with G, C, T standing for guanine, cytosine and thymine). In CHO cells transfected with adenine receptor it inhibits forskolin-stimulated cAMP formation. Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry. Adenine is used as an active component of boron-deficient media to grow yeast in order to assess whether yeast growth is stimulated by boron. It is useful as a local antiseptic and vitamin B4. Further, it is used in the microbial determination of niacin. It is also employed as a food supplement for adult rats to investigate the effects of dietary adenine overload.

References: Cell. 2015 May 7; 161(4):710-3; Bioessays. 2016 Jan; 38(1):27-40.

Related CAS#: 2922-28-3 (Adenine HCl); 321-30-2(Adenine sulfate); 700-49-2(2-Fluoroadenine); 5142-23-4 (3-Methyladenine, NSC 66389; NSC-66389); 935-69-3 (7-Methyladenine); 1123-54-2 (8-Azaadenine); 4261-14-7 (9-Benzyladenine); 2715-68-6 (9-Ethyladenine); 4185-03-9(9-Xylosyladenine); 715-91-3 Adenine, 9-cyclopentyl- (8CI); 1214-39-7(Benzyladenine); 23918-98-1 (Eritadenine; Lentinacin; Lentysine; D-Eritadenine); 17019-46-4 (Erythrofuranosyladenine, 9-beta-D-Erythrofuranosyladenine, 9-beta-D-Erythrofuranosyladenine, ETA); 938-55-6 (N(6), N(6)-Dimethyladenine); 57818-88-9 (1-Deaza-fad); 958-09-8(2'-Deoxyadenosine; NSC 141848; NSC141848; NSC-141848); 1492-61-1 (2-Fluoro-ADP; ADP-beta-F); 475193-31-8 (2-MeS-ADP); 84-21-9 (3'-Adenylicacid); 120241-79-4 (3-TYP); 3414-62-8 (6-Hydroxyadenosine); 6055-72-7 (Adenine monohydrochloride hemihydrate)