InvivoChem Cat #:V11731CAS #:58-73-1Purity >=98%Description: DiphenhydramineHCl is a potent and first-generation histamine H1 receptor antagonistand an antiemetic that is used in various allergic conditions such asrhinitis, urticaria and conjunctivitis. Diphenhydramine blockstetrodotoxin-sensitive (TTX-S) and tetrodotoxin-resistant (TTX-R) sodiumcurrents with K(d) values of 48 mM and 86 mM, respectively, at aholding potential of -80 mV. Diphenhydramine shifts theconductance-voltage curve for TTX-S sodium currents in the depolarizingdirection but has little effect on that for TTX-R sodium currents.
References: Brain Res. 2000 Oct 27; 881(2):190-8; Oncol Res. 2004; 14(7-8):363-72.
Related CAS #:147-24-0 (HCl) 58-73-1 (free base)
Description: DiphenhydramineHCl is a potent and first-generation histamine H1 receptor antagonistand an antiemetic that is used in various allergic conditions such asrhinitis, urticaria and conjunctivitis. Diphenhydramine blockstetrodotoxin-sensitive (TTX-S) and tetrodotoxin-resistant (TTX-R) sodiumcurrents with K(d) values of 48 mM and 86 mM, respectively, at aholding potential of -80 mV. Diphenhydramine shifts theconductance-voltage curve for TTX-S sodium currents in the depolarizingdirection but has little effect on that for TTX-R sodium currents.
Description:References: Brain Res. 2000 Oct 27; 881(2):190-8; Oncol Res. 2004; 14(7-8):363-72.
References:Related CAS #:147-24-0 (HCl) 58-73-1 (free base)