aripiprazole-monohydrate

Description: Aripiprazolemonohydrate (also known as OPC-14597) is a novel atypical antipsychotic drug thatis reported to be a high-affinity 5-HT receptor partial agonist. It is adopamine-serotonin system stabilizer with potent partial agonistactivity at dopamine D2 and 5-HT1A receptors and antagonist activity at5-HT2A receptors. In addition, aripiprazole has been reported to labelwith the agonist 125I7-OH-PIPAT and with the antagonist 3Hspiperonewith 0.34+/-0.02nM and 0.70+/-0.22nM, respectively.

References: J Pharmacol Exp Ther. 2002 Jul; 302(1):381-9; Biochem Biophys Res Commun. 1999 Dec 20; 266(2):560-3.

Related CAS #: 129722-25-4Dehydroaripiprazole (OPC-14857; DM-14857); 1089115-06-9 (AripiprazoleD8); 1259305-26-4 (Aripiprazole cavoxil); 1259305-29-7 (Aripiprazolelauroxil); 851220-85-4 (Aripiprazole monohydrate)