InvivoChem Cat #:V0852CAS #:128794-94-5; Purity >=98%Description: Mycophenolate Mofetil (Cellcept, Mycophenolic acid, Myfortic, RS-61443), an antimetabolite immunosuppressant, is a potent, non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively. Mycophenolic acid is an immunosuppressant drug used to prevent rejection in organ transplantation. Mycophenolate mofetil is an ester prodrug of the active immunosuppressant mycophenolic acid (MPA). MPA also produces the concentration-dependent inhibition of proliferation of ConA-stimulated T cells, LPS-stimulated B cells and alloantigen-specific T cells.
Description: References: Int Immunopharmacol. 2010 Jan; 10(1):91-7; Clin Exp Dermatol. 2012 Jan; 37(1):48-54.
References:Related CAS: 116680-01-4 (HCl); 24280-93-1 (Mycophenolic acid; Mycophenolate; RS-61443); 128794-94-5 (free acid)