nu1025

Description: NU1025 is a novel, potent and selective inhibitor of poly(ADP-ribose) polymerase (PARP) inhibitor with potential anticancer activity. It shows potent antiproliferative activity against various cancer cells and high in vivo antitumor efficacy as well. NU1025 ia able to potentiate the cytotoxicity of a diverse set of anti-cancer agents in L1210 cells.

References: Life Sci. 2006 Nov 10; 79(24):2293-302.

Synonym: NU 1025; NU1025; NU-1025.

Chemical Name: 8-Hydroxy-2-methyl-4(3H)-quinazolinone

InChi Key: YJDAOHJWLUNFLX-UHFFFAOYSA-N

InChi Code: InChI=1S/C9H8N2O2/c1-5-10-8-6(9(13)11-5)3-2-4-7(8)12/h2-4, 12H, 1H3, (H, 10, 11, 13)

SMILES Code: O=C1NC(C)=NC2=C1C=CC=C2O