ArtNr |
HY-N6939-10mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
82508-31-4 |
Menge |
10 mg |
Quantity options |
100 mg
10mM/1mL
10 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
99.47 |
Formula |
C23H28O8 |
Citations |
[1]Zhou BN, et al. Some progress on the chemistry of natural bioactive terpenoids from Chinese medicinal plants. Mem Inst Oswaldo Cruz. 1991;86 Suppl 2:219-26.<br>[2]Wang WC, et al. [Endocrine activity of pseudolaric acids A and B and their effects on sex hormones, prostaglandins, uteri, and fetuses]. Zhongguo Yao Li Xue Bao. 1991 Mar;12(2):187-90.<br>[3]Wei N, et al. The immunosuppressive activity of pseudolaric acid B on T lymphocytes in vitro. Phytother Res. 2013 Jul;27(7):980-5.<br>[4]Yu J, et al. Pseudolaric acid B inhibits the secretion of hepatitis B virus. Oncol Rep. 2017 Jan;37(1):519-525.<br>[5]Yu J, et al. Pseudolaric acid B activates autophagy in MCF-7 human breast cancer cells to prevent cell death. Oncol Lett. 2016 Mar;11(3):1731-1737. |
Smiles |
O=C(C1=CC[C@@]([C@@](CC1)(OC(C)=O)[C@]2([H])[C@@](C)(/C=C/C=C(C(O)=O)\C)O3)(CC2)C3=O)OC |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
82508-31-4 |
Lieferbar |
|
Product Description |
Pseudolaric Acid B is a diterpene isolated from the root of Pseudolarix kaempferi (pinaceae), has anti-cancer, antifungal, and antifertile activities, and shows immunosuppressive activity on T lymphocytes[1][2][3]. Pseudolaric Acid B inhibits hepatitis B virus (HBV) secretion through apoptosis and cell cycle arrest. Pseudolaric Acid B induces autophagy[4][5]. |
StorageTemperature |
4°C (Powder, protect from light) |
Shipping |
Room Temperature |
Manufacturers Applications |
Neuroscience-Neurodegeneration |
MolecularWeight |
432.46 |
Clinical_Information |
No Development Reported |
Manufacturers Research Area |
Cancer; Infection; Inflammation/Immunology |
Solubility |
DMSO : 50 mg/mL (ultrasonic) |
Manufacturers Target |
Apoptosis; Autophagy; Ferroptosis; Fungal; HBV |
Pathway |
Anti-infection; Apoptosis; Autophagy |
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