ArtNr |
HY-N6725-5mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
10048-13-2 |
Menge |
5 mg |
Quantity options |
1 mg
5 mg
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
99.74 |
Formula |
C18H12O6 |
Citations |
[1]Tong YF, et al. Cyclin-Dependent Kinase Inhibitor p21WAF1/CIP1 Facilitates the Development of CardiacHypertroph. Cell Physiol Biochem. 2017;42(4):1645-1656.<br>[2]Schroeder HW, et al. Production of sterigmatocystin by some species of the genus Aspergillus and its toxicity to chicken embryos. Appl Microbiol. 1975 Oct;30(4):589-91.<br>[3]Kusunoki M, et al. Long-term administration of the fungus toxin, sterigmatocystin, induces intestinal metaplasia and increases the proliferative activity of PCNA, p53, and MDM2 in the gastric mucosa of aged Mongolian gerbils. Environ Health Prev Med. 2011 Jul;16(4):224-31.<br>[4]Zhang D, et al. Sterigmatocystin-induced DNA damage triggers G2 arrest via an ATM/p53-related pathway in human gastric epithelium GES-1 cells in vitro. PLoS One. 2013 May 21;8(5):e65044. |
Smiles |
O=C1C2=C(OC3=C1C(O)=CC=C3)C4=C(O[C@]5([H])[C@@]4([H])C=CO5)C=C2OC |
ECLASS 5.1 |
30220300 |
ECLASS 6.1 |
30220300 |
ECLASS 8.0 |
32160605 |
ECLASS 9.0 |
32160605 |
ECLASS 10.0.1 |
32160490 |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
10048-13-2 |
Lieferbar |
|
Product Description |
Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor[1][2]. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals[3]. |
StorageTemperature |
4°C (Powder, protect from light) |
Shipping |
Room Temperature |
Manufacturers Applications |
Cancer-programmed cell death |
MolecularWeight |
324.28 |
Clinical_Information |
No Development Reported |
Manufacturers Research Area |
Cancer; Infection |
Solubility |
DMSO : 25 mg/mL (ultrasonic; warming; heat to 80°C) |
Manufacturers Target |
Antibiotic; Apoptosis; Bacterial; DNA/RNA Synthesis; Endogenous Metabolite |
Isoform |
Human Endogenous Metabolite; Microbial Metabolite |
Pathway |
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease |
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