ArtNr |
HY-N3841-50mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
62218-08-0 |
Menge |
50mg |
Quantity options |
100mg
10mM*1 mL
10 mg
1 mg
50mg
5 mg
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
98.0 |
Citations |
[1]Huang C, et al. ε-Viniferin and α-viniferin alone or in combination induced apoptosis and necrosis in osteosarcoma and non-small cell lung cancer cells. Food Chem Toxicol. 2021 Dec;158:112617.<br>[2]Chiou WC, et al. α-Viniferin and ε-Viniferin Inhibited TGF-β1-Induced Epithelial-Mesenchymal Transition, Migration and Invasion in Lung Cancer Cells through Downregulation of Vimentin Expression. Nutrients. 2022 May 30;14(11):2294.<br>[3]Liao HR, et al. The anti-inflammatory effect of ε-viniferin by specifically targeting formyl peptide receptor 1 on human neutrophils. Chem Biol Interact. 2021 Aug 25;345:109490.<br>[4]Zhang S, et al. Neuroprotective mechanisms of ε-viniferin in a rotenone-induced cell model of Parkinson's disease: significance of SIRT3-mediated FOXO3 deacetylation. Neural Regen Res. 2020 Nov;15(11):2143-2153. <br>[5]Ohara K, et al. ε-Viniferin, a resveratrol dimer, prevents diet-induced obesity in mice. Biochem Biophys Res Commun. 2015 Dec 25;468(4):877-82.<br>[6]Piver B, et al. Differential inhibition of human cytochrome P450 enzymes by epsilon-viniferin, the dimer of resveratrol: comparison with resveratrol and polyphenols from alcoholized beverages. Life Sci. 2003 Jul 18;73(9):1199-213.<br>[7]XAVIER VITRAC, et al. Determination of Stilbenes (δ-viniferin, trans-astringin, trans-piceid, cis- and trans-resveratrol, E-viniferin) in Brazilian Wines. J. Agric. Food Chem. 2005, 53, 5664−5669. |
Smiles |
OC1=CC([C@H]2[C@H](C3=CC=C(O)C=C3)OC4=CC(O)=CC(/C=C/C5=CC=C(O)C=C5)=C24)=CC(O)=C1 |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
epsilon-Viniferin |
Lieferbar |
|
Product Description |
ε-Viniferin (epsilon-Viniferin), the dimer of Resveratrol and can be isolated from Vitis vinifera, displays a potent inhibitory for all the CYP activities, with Ki values from 0.5-20 μM. ε-Viniferin possesses potent antioxidant, anti-inflammatory, anti-diabetic, and anti-neurodegenerative capacity[1][2][3]. |
StorageTemperature |
4°C (Powder, sealed storage, away from moisture and light) |
Shipping |
Room Temperature |
Manufacturers Applications |
COVID-19-immunoregulation |
MolecularWeight |
454.47 |
Clinical_Information |
No Development Reported |
Manufacturers Research Area |
Metabolic Disease; Inflammation/Immunology; Neurological Disease |
Solubility |
10 mM in DMSO |
Manufacturers Target |
Cytochrome P450 |
Isoform |
CYP1; CYP2; CYP3; CYP4 |
Pathway |
Metabolic Enzyme/Protease |
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