Punicalin

ArtNr	HY-N0639-5mg
Hersteller	MedChem Express
CAS-Nr.	65995-64-4
Menge	5 mg
Quantity options	10 mg 1 mg 20 mg 5 mg
Kategorie	Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	99.89
Formula	C34H22O22
Citations	[1]Lin CC, et al. Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats. Am J Chin Med. 1999;27(3-4):371-6.<br/>[2]Liu C, et al. Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA. Antiviral Res. 2016 Oct;134:97-107.<br/>[3]Shen R, et al. Punicalin Ameliorates Cell Pyroptosis Induced by LPS/ATP Through Suppression of ROS/NLRP3 Pathway. J Inflamm Res. 2021 Mar 5;14:711-718.<br/>[4]ang T, et al. Punicalin Alleviates OGD/R-Triggered Cell Injury via TGF-β-Mediated Oxidative Stress and Cell Cycle in Neuroblastoma Cells SH-SY5Y. Evid Based Complement Alternat Med. 2021 Feb 12;2021:6671282.<br/>[5]Ji W, et al. Punicalin attenuates LPS-induced acute lung injury by inhibiting inflammatory cytokine production and MAPK/NF-κB signaling in mice. Heliyon. 2023 Apr 10;9(4):e15434.<br/>[6]Satomi H, et al. Carbonic anhydrase inhibitors from the pericarps of Punica granatum L. Biol Pharm Bull. 1993 Aug;16(8):787-90.<br/>[7] Suručić R, et al. Pomegranate peel extract polyphenols attenuate the SARS-CoV-2 S-glycoprotein binding ability to ACE2 Receptor: In silico and in vitro studies. Bioorg Chem. 2021 Sep;114:105145.
Smiles	O=C1C(C(C(C(O)=C(O)C(O)=C2)=C2C(OC(C3O)C(O)C(O)C=O)=O)=C(O)C(O)=C4OC5=O)=C4C6=C5C(C7=C(C(OC3)=O)C=C(O)C(O)=C7O)=C(O)C(O)=C6O1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	65995-64-4
Lieferbar
Product Description	Punicalin is a species that can be isolated from the leaves of Punica granatum. Punicalin is an active molecule against hepatitis b virus (HBV). Punicalin can induce pyroptosis. Punicalin is a Carbonic anhydrase inhibitor. Punicalin blocks the binding of S-glycoprotein and ACE2 receptors. Pnuicalin has anti-inflammatory, antioxidant and antiviral activity[1][2][3][4][5][6][7].
StorageTemperature	4°C (Powder, stored under nitrogen)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-anti-virus
MolecularWeight	782.53
Clinical Information	No Development Reported
Manufacturers Research Area	Infection; Inflammation/Immunology
Solubility	DMSO : 50 mg/mL (ultrasonic)\|H2O : 50 mg/mL (ultrasonic)
Target	Carbonic Anhydrase; HBV; Pyroptosis
Manufacturers Target	Carbonic Anhydrase; HBV; Pyroptosis
Manufacturers Pathway	Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease
Manufacturers Product type	Natural Products

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