ArtNr |
HY-N0455-5g |
Hersteller |
MedChem Express
|
CAS-Nr. |
74-79-3 |
Menge |
5 g |
Quantity options |
100 g
10 mM/1 mL
1 g
500 g
500 mg
5 g
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
99.89 |
Formula |
C6H14N4O2 |
Citations |
[1]Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45. [2]Bakker J, et al. Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med. 2004 Jan;32(1):1-12. [3]Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17. [4]Mizunuma T, et al. Effects of injecting excess arginine on rat pancreas. J Nutr. 1984 Mar;114(3):467-71. [5]Siriviriyakul P, et al. Effects of curcumin on oxidative stress, inflammation and apoptosis in L-arginine induced acute pancreatitis in mice. Heliyon. 2019 Aug 27;5(8):e02222. |
Smiles |
N[C@@H](CCCNC(N)=N)C(O)=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
L-Arginine |
Versandbedingung |
Raumtemperatur |
Lieferbar |
|
Manufacturer - Type |
Natural Products |
Manufacturer - Applications |
Metabolism-protein/nucleotide metabolism |
Manufacturer - Targets |
Endogenous Metabolite; NO Synthase |
Shipping Temperature |
Room Temperature |
Storage Conditions |
Store at room temperature 3 years |
Molecular Weight |
174.20 |
Product Description |
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis[1][2][3][4][5]. |
Manufacturer - Research Area |
Cardiovascular Disease; Cancer |
Solubility |
H2O : 50 mg/mL (ultrasonic) |
Manufacturer - Pathway |
Immunology/Inflammation; Metabolic Enzyme/Protease |
Isoform |
eNOS; Human Endogenous Metabolite; Microbial Metabolite |
Clinical information |
Launched |
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