ArtNr |
HY-N0148A-5g |
Hersteller |
MedChem Express
|
CAS-Nr. |
207671-50-9 |
Menge |
5g |
Quantity options |
10g
10mM*1 mL
500 mg
5g
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
98.99 |
Citations |
[1]Ghorbani A. Mechanisms of antidiabetic effects of flavonoid rutin. Biomed Pharmacother. 2017;96:305-312.<br>[2]Habtemariam S. Rutin as a Natural Therapy for Alzheimer's Disease: Insights into its Mechanisms of Action. Curr Med Chem. 2016;23(9):860-873.<br>[3]Xu PX, et al. Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation. Behav Brain Res. 2014;264:173-180.<br>[4]Abdel-Aleem GA, et al. Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signalling. Arch Physiol Biochem. 2018;124(4):367-377. |
Smiles |
O=C1C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)O2)O)O)O)=C(C4=CC=C(O)C(O)=C4)OC5=CC(O)=CC(O)=C15.O.[36/5] |
ECLASS 5.1 |
30220300 |
ECLASS 6.1 |
30220300 |
ECLASS 8.0 |
32160605 |
ECLASS 9.0 |
32160605 |
ECLASS 10.0.1 |
32160490 |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
Rutoside (hydrate); Quercetin 3-O-rutinoside (hydrate) |
Lieferbar |
|
Product Description |
Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress[1][2][3]. |
StorageTemperature |
4°C (Powder, protect from light) |
Shipping |
Room Temperature |
Manufacturers Applications |
Neuroscience-Neuromodulation |
MolecularWeight |
713.04 |
Clinical_Information |
Launched |
Manufacturers Research Area |
Cancer; Neurological Disease |
Solubility |
DMSO : 50 mg/mL (ultrasonic) |
Manufacturers Target |
Amyloid-β; Apoptosis; Autophagy; Endogenous Metabolite |
Pathway |
Apoptosis; Autophagy; Metabolic Enzyme/Protease; Neuronal Signaling |
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