Salsalate

ArtNr	HY-B1245-100mg
Hersteller	MedChem Express
CAS-Nr.	552-94-3
Menge	100 mg
Quantity options	100 mg 10mM/1mL 1 g 500 mg 5 g
Kategorie	Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Clon	N/A
Specific against	other
Purity	99.55
Formula	C14H10O5
Citations	[1]Murthy SN, et al. Effects of salsalate therapy on recovery from vascular injury in female Zucker fatty rats. Diabetes. 2010;59(12):3240-3246.<br/>[2]Scheiman JM, et al. Gastroduodenal mucosal damage with salsalate versus aspirin: results of experimental models and endoscopic studies in humans. Semin Arthritis Rheum. 1990;20(2):121-127.<br/>[3]González F, et al. Salicylate administration suppresses the inflammatory response to nutrients and improves ovarian function in polycystic ovary syndrome. Am J Physiol Endocrinol Metab. 2020;319(4):E744-E752.
Smiles	O=C(OC1=CC=CC=C1C(O)=O)C2=CC=CC=C2O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Salicylsalicylic acid; Disalicylic acid
Lieferbar
Product Description	Salsalate, a non-acetylated salicylate, is an effective antirheumatic agent that bypasses gastric absorption and also avoids cyclooxygenase inhibition. Salsalate has anti-inflammatory activity and reduces glucose levels, insulin resistance, and cytokine expression. Salsalate can be used in the research of type 2 diabetes[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	258.23
Clinical Information	Launched
Manufacturers Research Area	Inflammation/Immunology
Solubility	DMSO : ≥ 100 mg/mL
Target	Reactive Oxygen Species
Manufacturers Target	Reactive Oxygen Species
Manufacturers Pathway	Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Manufacturers Product type	Reference compound

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HY-B1245-100mg-safety-datasheet.pdf