Adenine

ArtNr	HY-B0152-500mg
Hersteller	MedChem Express
CAS-Nr.	73-24-5
Menge	500 mg
Quantity options	10mM/1mL 1 g 500 mg 5 g
Kategorie	Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	99.98
Formula	C5H5N5
Citations	[1]ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27.<br/>[2]Griffiths AJF, et al. An Introduction to Genetic Analysis. 7th edition. New York: W. H. Freeman; 2000. Structure of DNA.<br/>[3]Reader V. The assay of vitamin B(4). Biochem J. 1930;24(6):1827-31.<br/>[4]Yung-Jen Tsai, et al. Pharmacokinetics of Adenosine and Cordycepin, a Bioactive Constituent of Cordyceps sinensis in Rat. J Agric Food Chem 2010 Apr 28;58(8):4638-43.<br/>[5]Fatma F Mohamed, et al. Dentoalveolar Alterations in an Adenine‐Induced Chronic Kidney Disease Mouse Model. J Bone Miner Res. 2023 Aug;38(8):1192-1207.<br/>[6]Chien-Ning Hsu, et al. Sodium Thiosulfate Improves Hypertension in Rats with Adenine-Induced Chronic Kidney Disease. Antioxidants (Basel). 2022 Jan 11;11(1):147.
Smiles	NC1=C2N=CNC2=NC=N1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Adenine
Lieferbar
Product Description	Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[1][2][3].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	135.13
Clinical Information	Launched
Manufacturers Research Area	Cancer
Solubility	1M HCl : 20 mg/mL (ultrasonic)\|DMSO : ≥ 10 mg/mL\|H2O : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Target	DNA/RNA Synthesis; Endogenous Metabolite
Manufacturers Target	DNA/RNA Synthesis; Endogenous Metabolite
Isoform	Human Endogenous Metabolite; Microbial Metabolite
Manufacturers Pathway	Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Manufacturers Product type	Natural Products

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HY-B0152-500mg-safety-datasheet.pdf