Tigecycline

ArtNr	HY-B0117-100mg
Hersteller	MedChem Express
CAS-Nr.	220620-09-7
Menge	100 mg
Quantity options	100 mg 10mM/1mL 10 mg 200 mg 500 mg 50 mg 5 mg
Kategorie	Oncology Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Typ	Inhibitors
Clon	N/A
Specific against	other
Purity	99.95
Formula	C29H39N5O8
Citations	Adv Ther (Weinh). 2024 Jan 12.<br/>Animal Diseases. 02 November 2021.<br/>Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00470-19.<br/>Antimicrob Agents Chemother. 2023 Jan 23;e0145922.<br/>Antimicrob Agents Chemother. 2024 Jan 30:e0112023.<br/>Biomed Pharmacother. 2023 Nov 8:115856.<br/>Clin Exp Pharmacol Physiol. 2023 Apr 22.<br/>EBioMedicine. 2022 Apr;78:103943.<br/>Infect Drug Resist. 2020 Jul 28;13:2617-2629.<br/>Infect Drug Resist. 2021 Jun 30;14:2499-2507.<br/>Infect Drug Resist. 2023 Apr 17.<br/>Int J Antimicrob Agents. 2018 Aug;52(2):269-271.<br/>J Antibiot (Tokyo). 2022 Jun 27.<br/>Microb Pathog. 2020 Dec;149:104502.<br/>Microbiol Spectr. 2022 Dec 8;e0323822.<br/>Microbiol Spectr. 2023 May 4;e0071823.<br/>Microorganisms. 2024 Mar 13, 12(3), 575.<br/>Nat Commun. 2022 Mar 2;13(1):1116.<br/>SLAS Discov. 2020 Sep;25(8):895-905.<br/>Vet Microbiol. 2024 May, 292, 110046.<br/>World J Microbiol Biotechnol. 2024 Jun 6;40(8):233.<br/>Ann Lab Med. 2021 May 1;41(3):293-301.<br/>Emerg Microbes Infect. 2024 Dec;13(1):2321981.<br/>[1]Jitkova Y, et al. A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity. PLoS One. 2014 May 28;9(5):e95281.<br/>[2]Falagas ME, et al. Activity of TP-6076 against carbapenem-resistant Acinetobacter baumannii isolates collected from inpatients in Greek hospitals. Int J Antimicrob Agents. 2018 Aug;52(2):269-271.
Smiles	O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=C(NC(CNC(C)(C)C)=O)C=C4N(C)C)N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	GAR-936
Lieferbar
Product Description	Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL[1]. MIC50 and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively[2].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	585.65
Clinical Information	Launched
Manufacturers Research Area	Infection; Cancer
Solubility	DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O : 8.33 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Antibiotic; Autophagy; Bacterial
Manufacturers Target	Antibiotic; Autophagy; Bacterial
Manufacturers Pathway	Anti-infection; Autophagy
Manufacturers Product type	Reference compound

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HY-B0117-100mg-safety-datasheet.pdf