ArtNr |
HY-30152-10mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
2009-24-7 |
Menge |
10 mg |
Quantity options |
100 mg
10mM/1mL
10 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
99.75 |
Formula |
C11H6O4 |
Citations |
[1]Ma Z, et al. Metabolism and Metabolic Inhibition of Xanthotoxol in Human Liver Microsomes. Evid Based Complement Alternat Med. 2016;2016:5416509.<br/>[2]Ma Z, et al. Metabolism and Metabolic Inhibition of Xanthotoxol in Human Liver Microsomes. Evid Based Complement Alternat Med. 2016;2016:5416509.<br/>[3]He W, et al. Xanthotoxol exerts neuroprotective effects via suppression of the inflammatory response in a rat model of focal cerebral ischemia. Cell Mol Neurobiol. 2013 Jul;33(5):715-22.<br/>[4]Lee Y, et al. Anti-Inflammatory Effects of Psoralen Derivatives on RAW264.7 Cells via Regulation of the NF-κB and MAPK Signaling Pathways. Int J Mol Sci. 2022 May 22;23(10):5813. |
Smiles |
O=C1OC(C(C=C1)=C2)=C(O)C3=C2C=CO3 |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
8-Hydroxypsoralen |
Lieferbar |
|
Product Description |
Xanthotoxol (8-Hydroxypsoralen) It is a kind of fragrant bean substance, and it is a CYP450 inhibitor. Xanthotoxol has anti-inflammatory, anti-inflammatory, and 5-HT antagonistic and protective effects. Xanthotoxol inhibited CYP3A4 sum CYP1A2 IC50s separation 7.43 μM sum 27.82 μM. Xanthotoxol can pass through MAPK and NF-κB, inhibiting inflammation[1][2][3][4]. |
StorageTemperature |
-20°C, 3 years; 4°C, 2 years (Powder) |
Shipping |
Room Temperature |
Manufacturers Applications |
COVID-19-immunoregulation |
MolecularWeight |
202.16 |
Clinical Information |
No Development Reported |
Manufacturers Research Area |
Inflammation/Immunology; Neurological Disease |
Solubility |
DMSO : 100 mg/mL (ultrasonic) |
Target |
5-HT Receptor; Endogenous Metabolite; Reactive Oxygen Species |
Manufacturers Target |
5-HT Receptor; Endogenous Metabolite; Reactive Oxygen Species |
Isoform |
5-HT Receptor; Human Endogenous Metabolite |
Manufacturers Pathway |
GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB |
Manufacturers Product type |
Natural Products |
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