ArtNr |
HY-17422-500mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
59277-89-3 |
Menge |
500 mg |
Quantity options |
100 mg
10mM/1mL
500 mg
50 mg
|
Kategorie |
|
Typ |
Inhibitors |
Clon |
N/A |
Specific against |
other |
Purity |
99.34 |
Formula |
C8H11N5O3 |
Citations |
[1]Benedetti S, et, al. Acyclovir induces cell cycle perturbation and apoptosis in Jurkat leukemia cells, and enhances chemotherapeutic drug cytotoxicity. Life Sci. 2018 Dec 15;215:80-85.<br/>[2]Suzuki M, et, al. Synergistic antiviral activity of acyclovir and vidarabine against herpes simplex virus types 1 and 2 and varicella-zoster virus. Antiviral Res. 2006 Nov;72(2):157-61.<br/>[3]Li Z, et, al. Acyclovir treatment of skin lesions results in immune deviation in mice infected cutaneously with herpes simplex virus. Antivir Chem Chemother. 1999 Sep;10(5):251-7.<br/>[4]Lönnqvist B, et, al. Oral acyclovir as prophylaxis for bacterial infections during induction therapy for acute leukaemia in adults. The Leukemia Group of Middle Sweden. Support Care Cancer. 1993 May;1(3):139-44. |
Smiles |
O=C1NC(N)=NC2=C1N=CN2COCCO |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
Aciclovir; Acycloguanosine |
Lieferbar |
|
Product Description |
Acyclovir (Aciclovir) is a potent, orally active antiviral agent. Acyclovir has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir induces cell cycle perturbation and apoptosis. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[1][2][3][4]. |
StorageTemperature |
-20°C, 3 years; 4°C, 2 years (Powder) |
Shipping |
Room Temperature |
Manufacturers Applications |
COVID-19-anti-virus |
MolecularWeight |
225.20 |
Clinical Information |
Launched |
Manufacturers Research Area |
Cancer; Infection |
Solubility |
DMSO : ≥ 50 mg/mL |
Target |
Antibiotic; Apoptosis; Bacterial; HSV |
Manufacturers Target |
Antibiotic; Apoptosis; Bacterial; HSV |
Isoform |
HSV-1; HSV-2 |
Manufacturers Pathway |
Anti-infection; Apoptosis |
Manufacturers Product type |
Reference compound |
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