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Sodium 4-phenylbutyrate Europäischer Partner

ArtNr HY-15654-100mg
Hersteller MedChem Express
CAS-Nr. 1716-12-7
Menge 100 mg
Quantity options 100 mg 10mM/1mL 200 mg
Kategorie
Typ Inhibitors
Clon N/A
Specific against other
Purity 99.96
Formula C10H11NaO2
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October 4th, 2022.<br/>Respir Res. 2023 Jun 2;24(1):149.<br/>Sci Immunol. 2023 Sep 29;8(87):eabq2424.<br/>Sci Rep. 2023 Jan 13;13(1):693.<br/>Sci Rep. 2023 Jan 20;13(1):1147.<br/>Sci Rep. 2023 Nov 9;13(1):19438.<br/>Sci Total Environ. 2023 Jun 1;164620.<br/>Sci Total Environ. 2024 Apr 20:172582.<br/>Sci Total Environ. 2024 Jan 17:915:170129.<br/>Small. 2022 Dec 4;e2204310.<br/>Toxicol In Vitro. 2022: 105534.<br/>Toxicology. 2022 May 15;473:153193.<br/>Toxicology. 2024 Apr 9:504:153800.<br/>Vet Microbiol. 2021 Feb;253:108959.<br/>Vet Microbiol. 2023 Jan 24;279:109666.<br/>Vet Microbiol. 2024 May, 292, 110051.<br/>Vet Res. 2024 Jun 14;55(1):78.<br/>Viruses. 2023, 15(2), 534.<br/>[1]Chang TH, et al. Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. Clin Cancer Res. 2002 Apr;8(4):1206-12.<br/>[2]Frouco G, et, al. Sodium phenylbutyrate abrogates African swine fever virus replication by disrupting the virus-induced hypoacetylation status of histone H3K9/K14. Virus Res. 2017 Oct 15;242:24-29.<br/>[3]Park HJ, et al. 4-Phenylbutyric acid protects against lipopolysaccharide-induced bone loss by modulating autophagy in osteoclasts. Biochem Pharmacol. 2018 May;151:9-17.
Smiles O=C(O[Na])CCCC1=CC=CC=C1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 4-PBA (sodium); 4-Phenylbutyric acid (sodium); Benzenebutyric acid (sodium)
Lieferbar
Product Description
Sodium 4-phenylbutyrate (4-PBA sodium) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research[1].
StorageTemperature
4°C (Powder, sealed storage, away from moisture)
Shipping
Room Temperature
Manufacturers Applications
Cancer-programmed cell death
MolecularWeight
186.18
Clinical Information
Launched
Manufacturers Research Area
Cancer
Solubility
H2O : 100 mg/mL (ultrasonic)
Target
Apoptosis; Autophagy; HDAC
Manufacturers Target
Apoptosis; Autophagy; HDAC
Isoform
HDAC
Manufacturers Pathway
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics
Manufacturers Product type
Reference compound

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 mg
Lieferbar: In stock
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