ArtNr |
HY-15129-100mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
407-41-0 |
Menge |
100 mg |
Quantity options |
100 mg
10 mM/1 mL
50 mg
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
98.0 |
Formula |
C3H8NO6P |
Citations |
[1]Kang HJ, et al. Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptors. J Biol Chem. 2015 Jan 30;290(5):2870-8. [2]Kang HJ, et al. Selectivity and evolutionary divergence of metabotropic glutamate receptors for endogenous ligands and G proteins coupled to phospholipase C or TRP channels. J Biol Chem. 2014 Oct 24;289(43):29961-74. [3]Bailey TJ, et al. The inhibitor of phagocytosis, O-phospho-L-serine, suppresses Müller glia proliferation and cone cell regeneration in the light-damaged zebrafish retina. Exp Eye Res. 2010 Nov;91(5):601-12. |
Smiles |
OP(OC[C@@H](C(O)=O)N)(O)=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
L-Serine O-phosphate, L-SOP |
Versandbedingung |
Raumtemperatur |
Lieferbar |
|
Manufacturer - Type |
Natural Products |
Manufacturer - Applications |
Neuroscience-Neuromodulation |
Manufacturer - Targets |
Endogenous Metabolite; mGluR |
Shipping Temperature |
Room Temperature |
Storage Conditions |
-20°C, 3 years; 4°C, 2 years (Powder) |
Molecular Weight |
185.07 |
Product Description |
O-Phospho-L-serine is the immediate precursor to L-cystein in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1]. |
Manufacturer - Research Area |
Neurological Disease |
Solubility |
DMSO : < 1 mg/mL|H2O : 25 mg/mL (ultrasonic) |
Manufacturer - Pathway |
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling |
Isoform |
Human Endogenous Metabolite; mGluR1; mGluR2; mGluR4; mGluR6; mGluR7; mGluR8 |
Clinical information |
No Development Reported |
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