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L-Glutamic acid

L-Glutamic acid

ArtNr	HY-14608-100mg
Hersteller	MedChem Express
CAS-Nr.	56-86-0
Menge	100 mg
Quantity options	100 mg 10mM/1mL 1 g 500 mg 5 g
Kategorie	Food Safety Inhibitors & Compound Libraries Small Molecules Amino Acid Analysis
Typ	Inhibitors
Specific against	other
Purity	99.84
Citations	J Transl Med. 2024 Feb 18;22(1):178.<br>Neurochem Int. 2023 Jul 24;105587.<br>Redox Biol. 2024 Mar 4:71:103112.<br>Res Sq. 2024 May 20.<br>[1] Liberatore F, et al. Permissive role for mGlu1 metabotropic glutamate receptors in excitotoxic retinal degeneration. Neuroscience. 2017 Nov 5;363:142-149.<br>[2]Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7.<br>[3]Boga Pekmezekmek A, et al. L-Glutamic acid monosodium salt reduces the harmful effect of lithium on the development of Xenopus laevis embryos. Environ Sci Pollut Res Int. 2020 Nov;27(33):42124-42132.<br>[4]Croce N, et al. Hydrochloric acid alters the effect of L-glutamic acid on cell viability in human neuroblastoma cell cultures. J Neurosci Methods. 2013 Jul 15;217(1-2):26-30.<br>[5]Salyha N, et al. Protective role of l-glutamic acid and l-cysteine in mitigation the chlorpyrifos-induced oxidative stress in rats. Environ Toxicol Pharmacol. 2018 Dec;64:155-163.
Smiles	OC(CC[C@H](N)C(O)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	56-86-0
Lieferbar
Product Description	L-Glutamic acid is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid can be used in the study of neurological diseases[1][2][3][4][5].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	147.13
Clinical_Information	Launched
Manufacturers Research Area	Neurological Disease
Solubility	DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O : 6.25 mg/mL (ultrasonic)
Manufacturers Target	Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR
Isoform	AMPA Receptor; Human Endogenous Metabolite; Microbial Metabolite
Pathway	Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

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HY-14608-100mg-safety-datasheet.pdf