ArtNr |
HY-11018-50mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
106266-06-2 |
Menge |
50 mg |
Quantity options |
100 mg
10mM/1mL
10 mg
500 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Inhibitors |
Clon |
N/A |
Specific against |
other |
Purity |
99.92 |
Formula |
C23H27FN4O2 |
Citations |
[1]Nyberg S, et al. 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone. Psychopharmacology (Berl). 1993;110(3):265-72.<br/>[2]Zhu HJ, et al. Risperidone and paliperidone inhibit p-glycoprotein activity in vitro. Neuropsychopharmacology. 2007 Apr;32(4):757-64.<br/>[3]Chen ML, et al. Risperidone modulates the cytokine and chemokine release of dendritic cells and induces TNF-α-directed cell apoptosis in neutrophils. Int Immunopharmacol. 2012 Jan;12(1):197-204.<br/>[4]Bardgett ME, et al. Adult rats treated with risperidone during development are hyperactive. Exp Clin Psychopharmacol. 2013 Jun;21(3):259-67. |
Smiles |
O=C1C(CCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)=C(C)N=C5N1CCCC5 |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
R 64 766 |
Lieferbar |
|
Product Description |
Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively. |
StorageTemperature |
-20°C, 3 years; 4°C, 2 years (Powder) |
Shipping |
Room Temperature |
Manufacturers Applications |
Neuroscience-Neuromodulation |
MolecularWeight |
410.48 |
Clinical Information |
Launched |
Manufacturers Research Area |
Neurological Disease |
Solubility |
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C) |
Target |
5-HT Receptor; Dopamine Receptor; P-glycoprotein |
Manufacturers Target |
5-HT Receptor; Dopamine Receptor; P-glycoprotein |
Isoform |
5-HT2 Receptor; D2 Receptor |
Manufacturers Pathway |
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling |
Manufacturers Product type |
Reference compound |
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