Vinculin, Human (HEK293, His)

Vinculin Protein, an actin-binding protein, is crucial for cell adhesion, morphology, and mechanosensing. It regulates E-cadherin expression and enhances mechanosensing. Vinculin forms complexes with THSD1, PTK2/FAK1, TLN1, and VCL, and interacts with APBB1IP, NRAP, CTNNB1, SYNM, SORBS1, and CTNNA1. Its interaction with CTNNA1 is necessary for localization to cell-cell junctions. Vinculin also binds to ACTN4, causing conformational changes. Vinculin Protein, Human (HEK293, His) is the recombinant human-derived Vinculin protein, expressed by HEK293 , with C-His labeled tag. The total length of Vinculin Protein, Human (HEK293, His) is 1066 a.a., with molecular weight of ~115 kDa.

Approximately 115 kDa