ArtNr |
HY-P0206-1mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
58-82-2 |
Menge |
1 mg |
Quantity options |
100 mg
10mM*1 mL
10 mg
1 mg
25 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
99.92 |
Formula |
C50H73N15O11 |
Citations |
[1]Hornig B, et al. Role of bradykinin in mediating vascular effects of angiotensin-converting enzyme inhibitors inhumans. Circulation. 1997 Mar 4;95(5):1115-8.<br/>[2]Wang G, et al. Bradykinin stimulates IL-6 production and cell invasion in colorectal cancer cells. Oncol Rep. 2014 Oct;32(4):1709-14.<br/>[3]Dong R, et al. Exogenous Bradykinin Inhibits Tissue Factor Induction and Deep Vein Thrombosis via Activating the eNOS/Phosphoinositide 3-Kinase/Akt Signaling Pathway. Cell Physiol Biochem. 2015;37(4):1592-606.<br/>[4]Uchida S, et al. Afferent fibers involved in the bradykinin-induced cardiovascular reflexes from the ovary in rats. Auton Neurosci. 2015 Dec;193:57-62.<br/>[5]Liu LT, et al. Effect of vascular bradykinin on pancreatic microcirculation and hemorheology in rats with severe acute pancreatitis. Eur Rev Med Pharmacol Sci. 2015;19(14):2646-50. |
Smiles |
O=C(N1[C@@H](CCC1)C(NCC(N[C@H](C(N[C@@H](CO)C(N2[C@@H](CCC2)C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CC3=CC=CC=C3)=O)=O)=O)CC4=CC=CC=C4)=O)=O)[C@H]5N(CCC5)C([C@@H](N)CCCNC(N)=N)=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Lieferbar |
|
Product Description |
Bradykinin is an effective endothelium-dependent vasodilator that can lower blood pressure. Bradykinin can induce contraction of bronchial and intestinal non-vascular smooth muscle, increase vascular permeability, and participate in the mechanism of pain[1][2][3][4][5]. |
StorageTemperature |
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture) |
Shipping |
Blue Ice |
Manufacturers Applications |
COVID-19-immunoregulation |
MolecularWeight |
1060.21 |
Clinical Information |
Phase 4 |
Manufacturers Research Area |
Cardiovascular Disease; Endocrinology |
Solubility |
10 mM in DMSO|H2O : ≥ 100 mg/mL |
Target |
Bradykinin Receptor; Endogenous Metabolite; Ser/Thr Protease |
Manufacturers Target |
Bradykinin Receptor; Endogenous Metabolite; Ser/Thr Protease |
Isoform |
Bradykinin B2 Receptor (B2R); Human Endogenous Metabolite |
Manufacturers Pathway |
GPCR/G Protein; Metabolic Enzyme/Protease |
Manufacturers Product type |
Peptides |
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