ArtNr |
HY-N7140-50mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
506-26-3 |
Menge |
50 mg |
Quantity options |
10 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
99.74 |
Formula |
C18H30O2 |
Citations |
[1]Sergeant S, et al. Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes. Eur J Pharmacol. 2016 Aug 15;785:77-86. [2]Youn K, et al. Gamma-linolenic acid ameliorates Aβ-induced neuroinflammation through NF-κB and MAPK signalling pathways[J]. Journal of Functional Foods, 2018, 42: 30-37. [3]Andreoli Miyake J, et al. Gamma-Linolenic acid alters migration, proliferation and apoptosis in human and rat glioblastoma cells. Prostaglandins Other Lipid Mediat. 2020 Oct;150:106452. [4]Rahimi K, et al. The protective effects of Gamma-linolenic acid against indomethacin-induced gastric ulcer in rats[J]. British Journal of Nutrition, 2024, 131(11): 1844-1851. [5]Khan SA, et al. Gamma-linolenic acid ameliorated glycation-induced memory impairment in rats. Pharm Biol. 2017 Dec;55(1):1817-1823. |
Smiles |
CCCCC/C=C\C/C=C\C/C=C\CCCCC(O)=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
γ-Linolenic acid |
Similar products |
506-26-3 |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Manufacturer - Type |
Natural Products |
Manufacturer - Applications |
Metabolism-sugar/lipid metabolism |
Manufacturer - Targets |
Apoptosis; Endogenous Metabolite; ERK; JNK; NF-κB |
Shipping Temperature |
Blue Ice |
Storage Conditions |
-20°C (Powder, protect from light, stored under nitrogen) |
Molecular Weight |
278.43 |
Product Description |
Gamma-linolenic acid (γ-Linolenic acid) is an orally active unsaturated fatty acid. Gamma-linolenic acid exerts anti-inflammatory effects by inhibiting the NF-κB pathway and the phosphorylation of ERK1/2 and JNK. At the same time, it exerts anticancer effects by inducing apoptosis (Apoptosis) in cancer cells. Additionally, Gamma-linolenic acid also has antioxidant and memory-improving effects. It holds promise for research in the fields of inflammation, neurology, and cancer diseases[1][2][3][4][5]. |
Manufacturer - Research Area |
Cancer; Inflammation/Immunology; Neurological Disease |
Solubility |
DMSO : 100 mg/mL (ultrasonic) |
Manufacturer - Pathway |
Apoptosis; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt |
Isoform |
ERK1; ERK2; Human Endogenous Metabolite |
Clinical information |
Launched |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.