ArtNr |
HY-N7140-10mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
506-26-3 |
Menge |
10 mg |
Quantity options |
10 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
99.74 |
Formula |
C18H30O2 |
Citations |
[1]Sergeant S, et al. Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes. Eur J Pharmacol. 2016 Aug 15;785:77-86. [2]Youn K, et al. Gamma-linolenic acid ameliorates Aβ-induced neuroinflammation through NF-κB and MAPK signalling pathways[J]. Journal of Functional Foods, 2018, 42: 30-37. [3]Andreoli Miyake J, et al. Gamma-Linolenic acid alters migration, proliferation and apoptosis in human and rat glioblastoma cells. Prostaglandins Other Lipid Mediat. 2020 Oct;150:106452. [4]Rahimi K, et al. The protective effects of Gamma-linolenic acid against indomethacin-induced gastric ulcer in rats[J]. British Journal of Nutrition, 2024, 131(11): 1844-1851. [5]Khan SA, et al. Gamma-linolenic acid ameliorated glycation-induced memory impairment in rats. Pharm Biol. 2017 Dec;55(1):1817-1823. |
Smiles |
CCCCC/C=C\C/C=C\C/C=C\CCCCC(O)=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
γ-Linolenic acid |
Similar products |
506-26-3 |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Manufacturer - Type |
Natural Products |
Manufacturer - Applications |
Metabolism-sugar/lipid metabolism |
Manufacturer - Targets |
Apoptosis; Endogenous Metabolite; ERK; JNK; NF-κB |
Shipping Temperature |
Blue Ice |
Storage Conditions |
-20°C (Powder, protect from light, stored under nitrogen) |
Molecular Weight |
278.43 |
Product Description |
Gamma-linolenic acid (γ-Linolenic acid) is an orally active unsaturated fatty acid. Gamma-linolenic acid exerts anti-inflammatory effects by inhibiting the NF-κB pathway and the phosphorylation of ERK1/2 and JNK. At the same time, it exerts anticancer effects by inducing apoptosis (Apoptosis) in cancer cells. Additionally, Gamma-linolenic acid also has antioxidant and memory-improving effects. It holds promise for research in the fields of inflammation, neurology, and cancer diseases[1][2][3][4][5]. |
Manufacturer - Research Area |
Cancer; Inflammation/Immunology; Neurological Disease |
Solubility |
DMSO : 100 mg/mL (ultrasonic) |
Manufacturer - Pathway |
Apoptosis; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt |
Isoform |
ERK1; ERK2; Human Endogenous Metabolite |
Clinical information |
Launched |
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