ArtNr |
HY-N0005S-5mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
1246833-26-0 |
Menge |
5 mg |
Quantity options |
10 mg
1 ea
1 mg
5 mg
|
Kategorie |
|
Typ |
Molecules |
Specific against |
other |
Formula |
C21H14D6O6 |
Citations |
[1]Gao S, et al. Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion. Food Chem Toxicol. 2013 Jul 18. pii: S0278-6915(13)004.<br/>[2]Nasiri M, et al. Curcumin and Silibinin Inhibit Telomerase Expression in T47D Human Breast Cancer Cells. Asian Pac J Cancer Prev. 2013;14(6):3449-53.<br/>[3]Jiang H, et al. Antidepressant-like effects of curcumin in chronic mild stress of rats: Involvement of its anti-inflammatory action. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 20. pii: S0278-5846(13)00150-4.<br/>[4]Guo H, et al. Curcumin induces cell cycle arrest and apoptosis of prostate cancer cells by regulating the expression of IkappaBalpha, c-Jun and androgen receptor. Pharmazie. 2013 Jun;68(6):431-4.<br/>[5]Zhu X, et al. Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model. PLoS One. 2014 Mar 6;9(3):e91303. |
Smiles |
O=C(CC(/C=C/C1=CC=C(O)C(OC([2H])([2H])[2H])=C1)=O)/C=C/C2=CC=C(O)C(OC([2H])([2H])[2H])=C2 |
ECLASS 10.1 |
32169090 |
ECLASS 11.0 |
32169090 |
UNSPSC |
12000000 |
Alias |
Diferuloylmethane-d6; Natural Yellow 3-d6; Turmeric yellow-d6 |
Lieferbar |
|
Product Description |
Curcumin-d6is a deuterium labeled Curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase (HATs) and also shows inhibitory effects on NF-κB and MAPKs. |
Shipping |
Room temperature |
Manufacturers Applications |
Cancer-programmed cell death |
MolecularWeight |
374.42 |
Clinical Information |
No Development Reported |
Manufacturers Research Area |
Infection; Metabolic Disease; Inflammation/Immunology |
Solubility |
10 mM in DMSO |
Target |
Autophagy; Epigenetic Reader Domain; Ferroptosis; Histone Acetyltransferase; Influenza Virus; Keap1-Nrf2; Mitophagy |
Manufacturers Target |
Autophagy; Epigenetic Reader Domain; Ferroptosis; Histone Acetyltransferase; Influenza Virus; Keap1-Nrf2; Mitophagy |
Isoform |
CBP/p300 |
Manufacturers Pathway |
Anti-infection; Apoptosis; Autophagy; Epigenetics; NF-κB |
Manufacturers Product type |
Isotope-Labeled Compounds |
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