ArtNr |
HY-B0131-1mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
745-65-3 |
Menge |
1 mg |
Quantity options |
10mM*1 mL
10 mg
1 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
98.81 |
Formula |
C20H34O5 |
Citations |
[1]Kiriyama M, et, al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol. 1997 Sep;122(2):217-24.<br/>[2]Cattaneo MG, et, al. Alprostadil suppresses angiogenesis in vitro and in vivo in the murine Matrigel plug assay. Br J Pharmacol. 2003 Jan;138(2):377-85.<br/>[3]Hauck EW, et, al. Prostaglandin E1 long-term self-injection programme for treatment of erectile dysfunction--a follow-up of at least 5 years. Andrologia. 1999;31 Suppl 1:99-103. |
Smiles |
CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CCCCCCC(O)=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
Alprostadil; PGE1 |
Lieferbar |
|
Product Description |
Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases[1][2][3]. |
StorageTemperature |
4°C (Powder, stored under nitrogen) |
Shipping |
Room Temperature |
Manufacturers Applications |
Metabolism-protein/nucleotide metabolism |
MolecularWeight |
354.48 |
Clinical Information |
Launched |
Manufacturers Research Area |
Endocrinology; Cardiovascular Disease; Cancer |
Solubility |
DMSO : 100 mg/mL (ultrasonic)|Ethanol : 100 mg/mL (ultrasonic) |
Target |
Endogenous Metabolite; Prostaglandin Receptor |
Manufacturers Target |
Endogenous Metabolite; Prostaglandin Receptor |
Isoform |
EP; Human Endogenous Metabolite |
Manufacturers Pathway |
GPCR/G Protein; Metabolic Enzyme/Protease |
Manufacturers Product type |
Natural Products |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.