ArtNr |
HY-32329S-1mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
1795024-97-3 |
Menge |
1 mg |
Kategorie |
|
Typ |
Molecules |
Specific against |
other |
Formula |
C19H16D3N |
Citations |
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.<br>[2]Yamada K, Furukawa T. [Behavioral effects of a new antidepressant, setiptiline]. Nihon Yakurigaku Zasshi. 1991 Jan;97(1):31-9.<br>[3]Kamimura M, Aoba A, Yamaguchi N et al. The effect of age on plasma level of setiptiline maleate in depressed patients. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Oct;18(6):1015-26.<br>[4]Kuniyoshi M, Nakamura J, Miura C, Inanaga K. Effectiveness of concomitant setiptiline maleate (Tecipul) on negative symptoms of schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Mar;18(2):339-46.<br>[5]Niho T, Ito C, Shibutani Y, Hashizume H, Yamaguchi K. [Pharmacological properties of MO-8282, a novel antidepressant]. Nihon Yakurigaku Zasshi. 1986 Oct;88(4):309-20. |
Smiles |
C(N1CC2=C(C=3C(CC=4C2=CC=CC4)=CC=CC3)CC1)([2H])([2H])[2H] |
ECLASS 10.1 |
32169090 |
ECLASS 11.0 |
32169090 |
UNSPSC |
12000000 |
Lieferbar |
|
Product Description |
Setiptiline-d3 is the deuterium labeled Setiptiline. Setiptiline (Org-8282) is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine[1][2]. |
Shipping |
Room temperature |
Manufacturers Applications |
Neuroscience-Neuromodulation |
MolecularWeight |
264.38 |
Clinical_Information |
No Development Reported |
Manufacturers Research_Area |
Neurological Disease |
Solubility |
10 mM in DMSO |
Manufacturers Target |
5-HT Receptor; Adrenergic Receptor; Isotope-Labeled Compounds |
Pathway |
GPCR/G Protein; Neuronal Signaling; Others |
Manufacturers Product type |
Isotope-Labeled Compounds |
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