ArtNr |
HY-17573A-50mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
1631754-28-3 |
Menge |
50 mg |
Kategorie |
|
Typ |
Molecules |
Specific against |
other |
Purity |
99.86 |
Formula |
C47H73N11O14S |
Citations |
[1]Stella Chaviaras, et al. Assessing the antidepressant-like effects of carbetocin, an oxytocin agonist, using a modification of the forced swimming test. Psychopharmacology (Berl). 2010 May;210(1):35-43.<br>[2]Gerald Gimpl, et al. Binding domains of the oxytocin receptor for the selective oxytocin receptor antagonist barusiban in comparison to the agonists oxytocin and carbetocin. Eur J Pharmacol. 2005 Mar 7;510(1-2):9-16.<br>[3]David Feifel, et al. The effects of oxytocin and its analog, carbetocin, on genetic deficits in sensorimotor gating. Eur Neuropsychopharmacol. 2012 May;22(5):374-8. |
Smiles |
O=C([C@H](CSCCCC(N[C@H](C1=O)CC2=CC=C(OC)C=C2)=O)NC([C@@H](NC([C@](NC([C@](N1)([H])[C@@H](C)CC)=O)([H])CCC(N)=O)=O)CC(N)=O)=O)N(CCC3)[C@@H]3C(N[C@@H](CC(C)C)C(NCC(N)=O)=O)=O.CC(O)=O |
ECLASS 10.1 |
32169090 |
ECLASS 11.0 |
32169090 |
UNSPSC |
12000000 |
Lieferbar |
|
Product Description |
Carbetocin acetate, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a Ki of 7.1 nM. Carbetocin acetate has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (Ki=1.17 μM). Carbetocin acetate has the potential for postpartum hemorrhage research. Carbetocin acetate can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS[1][2][3]. |
StorageTemperature |
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen) |
Shipping |
Blue Ice |
Manufacturers Applications |
Metabolism-protein/nucleotide metabolism |
MolecularWeight |
1048.21 |
Clinical_Information |
Launched |
Manufacturers Research_Area |
Endocrinology; Neurological Disease |
Solubility |
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)|H2O : 10 mg/mL (ultrasonic; warming; heat to 60°C) |
Manufacturers Target |
Oxytocin Receptor |
Pathway |
GPCR/G Protein |
Manufacturers Product type |
Peptides |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.