ArtNr |
HY-17002-50mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
94055-76-2 |
Menge |
50 mg |
Quantity options |
100 mg
10 mM/1 mL
10 mM/1 mL
500 mg
50 mg
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
98.33 |
Formula |
C23H33NO7S2 |
Citations |
[1]Furonaka M, Hattori N, Tanimoto T, Senoo T, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Kohno N.
<br>Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice.
<br>J Pharmacol Exp Ther. 2009 Jan;328(1):55-61.<br/>[2]Yanagihara Y, et, al. Suppression of IgE production by IPD-1151T (suplatast tosilate), a new dimethylsulfonium agent: (2). Regulation of human IgE response. Jpn J Pharmacol. 1993 Jan;61(1):31-9.<br/>[3]Zhao GD, et, al. Effect of suplatast tosilate (IPD-1151T) on a mouse model of asthma: inhibition of eosinophilic inflammation and bronchial hyperresponsiveness. Int Arch Allergy Immunol. 2000 Feb;121(2):116-22.<br/>[4]Kurokawa M, et, al. Suppressive effects of anti-allergic agent suplatast tosilate (IPD-1151T) on the expression of co-stimulatory molecules on mouse splenocytes in vivo. Mediators Inflamm. 2001 Dec;10(6):333-7. |
Smiles |
C[S+](C)CCC(NC1=CC=C(C=C1)OCC(COCC)O)=O.CC2=CC=C(C=C2)S(=O)([O-])=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
IPD 1151T |
Lieferbar |
|
Product Description |
Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor which can inhibit both IL-4 and IL-5 production from Th2 cells and suppress IgE synthesis. Suplatast Tosilate is an anti-allergic agent. Suplatast Tosilate has antiasthmatic, anti-inflammatory and antifibrotic activity[1][2][3][4]. |
StorageTemperature |
4°C (Powder, sealed storage, away from moisture) |
Shipping |
Room Temperature |
Manufacturers Applications |
COVID-19-immunoregulation |
MolecularWeight |
499.64 |
Clinical Information |
Launched |
Manufacturers Research Area |
Inflammation/Immunology |
Solubility |
DMSO : ≥ 33 mg/mL|H2O : ≥ 100 mg/mL |
Target |
Interleukin Related |
Manufacturers Target |
Interleukin Related |
Isoform |
IL-13; IL-2; IL-4; IL-5 |
Manufacturers Pathway |
Immunology/Inflammation |
Manufacturers Product type |
Reference compound |
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