ArtNr |
HY-114360A-100mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
38411-85-7 |
Menge |
100 mg |
Quantity options |
100 mg
1 ea
50 mg
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
98.0 |
Formula |
C26H44NNaO6S |
Citations |
[1]Roda A, et al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat. Hepatology. 1998 Feb;27(2):520-5. <br/>[2]Angelico M, et al. Dissolution of human cholesterol gallstones in bile salt/lecithin mixtures: effect of bile salt hydrophobicity and various pHs. Scand J Gastroenterol. 1995 Dec;30(12):1178-85. <br/>[3]Angelico M, et al. Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat. Dig Dis Sci. 1994 Nov;39(11):2389-97. <br/>[4]Roda A, et al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat. Hepatology. 1998 Feb;27(2):520-5. <br/>[5]Solmon Kusuma S, et al. Antineoplastic activity of monocrotaline against hepatocellular carcinoma[J]. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents), 2014, 14(9): 1237-1248. |
Smiles |
C[C@@]12[C@]3([H])[C@](C[C@@H]([C@]1([H])C[C@@H](CC2)O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCC(NCCS(=O)(O[Na])=O)=O)C |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Lieferbar |
|
Product Description |
Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model. |
StorageTemperature |
4°C (Powder, sealed storage, away from moisture) |
Shipping |
Room Temperature |
MolecularWeight |
521.69 |
Clinical Information |
No Development Reported |
Manufacturers Research Area |
Inflammation/Immunology |
Solubility |
H2O : 62.5 mg/mL (ultrasonic) |
Target |
Interleukin Related; TNF Receptor |
Manufacturers Target |
Interleukin Related; TNF Receptor |
Isoform |
IL-6; TNFRSF1A/CD120a |
Manufacturers Pathway |
Apoptosis; Immunology/Inflammation |
Manufacturers Product type |
Biochemical Assay Reagents |
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