ArtNr |
HY-101410-5mg |
Hersteller |
MedChem Express
|
CAS-Nr. |
30344-00-4 |
Menge |
5 mg |
Quantity options |
100 mg
10 mM/1 mL
10 mg
25 mg
50 mg
5 mg
|
Kategorie |
|
Typ |
Inhibitors |
Specific against |
other |
Purity |
98.0 |
Formula |
C8H18N4O2 |
Citations |
[1]Bode-Böger SM,et al. Symmetrical dimethylarginine: a new combined parameter for renal function and extent ofcoronary artery disease. [2]Schepers E, et al. Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease.Clin J Am Soc Nephrol. 2011 Oct;6(10):2374-83. [3]Nabity MB, et al. Symmetric Dimethylarginine Assay Validation, Stability, and Evaluation as a Marker for the EarlyDetection of Chronic Kidney Disease in Dogs. J Vet Intern Med. 2015 Jul-Aug;29(4):1036-44. [4]Veldink H, et al. Effects of chronic SDMA infusion on glomerular filtration rate, blood pressure, myocardial function and renal histology in C57BL6/J mice. Nephrol Dial Transplant. 2013 Jun;28(6):1434-9. |
Smiles |
N[C@@H](CCC/N=C(NC)/NC)C(O)=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
Symmetric dimethylarginine, NG,NG'-Dimethyl-L-arginine |
Versandbedingung |
Raumtemperatur |
Lieferbar |
|
Manufacturer - Type |
Natural Products |
Manufacturer - Applications |
COVID-19-immunoregulation |
Manufacturer - Targets |
Endogenous Metabolite; NF-κB; NO Synthase |
Shipping Temperature |
Room Temperature |
Storage Conditions |
-20°C, 3 years; 4°C, 2 years (Powder) |
Molecular Weight |
202.25 |
Product Description |
SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing. |
Manufacturer - Research Area |
Inflammation/Immunology |
Solubility |
DMSO : 67.5 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic; warming; heat to 60°C) |
Manufacturer - Pathway |
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB |
Isoform |
Human Endogenous Metabolite |
Clinical information |
No Development Reported |