Carbenicillin Disodium Salt

Carbenicillin is a member of the penicillin β -lactam antibiotics. However, unlike most β -lactams, carbenicillin disodium is limited to primarily gram-negative bacteria including  Pseudomonas aeruginosaand common enteric species. It can be used in selection protocols and is often preferred over ampicillin due to its increased stability. This allows for less contamination of unwanted bacterial colonies.
In addition, carbenicillin has been used to regulate bacterial growth in plants, yielding low regeneration frequencies. It can be used in genetic transformation applications to select for  AmpR  transformed cells.
Carbenicillin’ s longstanding application as a gene selection antibiotic in plant biology, has a powerful new role in Genome editing utilizing the CRISPR/Cas9 system¹

α -carboxybenzylpenicillin

737.8 ° C at 760 mmHg 

Soluble in Water

+4° C

MFCD00077683

InChI=1S/ C17H18N2O6S.2Na/ c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8; ; / h3-7, 9-11, 14H, 1-2H3, (H, 18, 20)(H, 22, 23)(H, 24, 25); ; / q; 2*+1/ p-2/ t9?, 10-, 11+, 14-; ; / m1../ s1