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Biotinylated Human HLA-A*11:01&B2M&KRASG12D (VVVGADGVGK) Complex Protein (Monomer, MALS verified)

Biotinylated Human HLA-A*11:01&B2M&KRASG12D (VVVGADGVGK) Complex Protein (Monomer, MALS verified)

ArtNr	HLD-H82E9-200ug
Hersteller	ACROBiosystems
Menge	200 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Powder
Specific against	Human
Host	HEK293
Konjugat/Tag	Biotin, HIS, Avi
Purity	90%
Formula	PBS, pH7.4
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Lieferbar
Manufacturers Category	Protein / MABSol® Biotin Labeled Proteins
Description	Biotinylated Human HLA-A11:01&B2M&KRASG12D (VVVGADGVGK) Complex Protein (HLD-H82E9) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A11:01) & Ile 21 - Met 119 (B2M) & VVVGADGVGK peptide (Accession # Q5S3G3-1 (HLA-A*11:01) & P61769 (B2M) & VVVGADGVGK).
Molecule	HLA-A*1101 & B2M & KRASG12D (VVVGADGVGK)
Exp Region	Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVVGADGVGK peptide
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	36.0 kDa and 11.7 kDa
Characteristics	Biotinylated Human HLA-A*11:01&B2M&KRASG12D (VVVGADGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12D peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.0 kDa and 11.7 kDa. The protein migrates as 39-43 kDa and 12 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Alex Fluor labeled Human HLA-A1101 KRASG12D (VVVGADGVGK) complex protein is a complex of HLA-A1101 of the MHC Class I, B2M, and VVVGADGVGK peptide of the KRASG12D.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 200 ug

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Lieferung vsl. bis 27.09.2024

Express-Lieferung: 4 Tage sparen

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