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DsbC Set

ArtNr GFK-PF005-50ML-EX
Hersteller Cosmobio
Menge 25 x 2 ml
Quantity options 500 ul Equivalents 5 x 2 ml Equivalents 25 x 2 ml
Specific against other
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Manufacturer - Category
Protein Engineering/Cell Free Synthesis/Reconstituted/Disulfide Bond Supplements
Maker
GFK
Short Description
DsbC Set is a supplement for the PUREfrex® series reconstituted coupled transcription/translation systems, designed to promote synthesis of functional proteins that contain disulfide bonds. \\DsbC Set comprises E.coli disulfide bond isomerase (DsbC), which catalyzes disulfide bridge exchange reactions, and GSSG (oxidized glutathione) to create an oxidizing environment.
Description
Redox Environment Supplements Promote Disulfide Bond Formation
Formation of disulfide bonds is important for folding and stability of secretory proteins such as enzymes or antibodies. Disulfide bonds are usually formed by oxidation of sulfhydryl groups (SH-) of adjacent cysteine residues. Therefore, disulfide bond formation efficiency depends on redox state. Additionally, disulfide bond isomerase which can catalyze the exchange of disulfide bridges may be required for correct cysteine pairing.

Redox Supplement



DsbC Set comprises highly purified E. coli DsbC (a disulfide bond isomerase) which can catalyze disulfide bridge exchange, and GSSG (oxidized Glutathione) to enforce an oxidized environment.

Menge: 25 x 2 ml
Lieferbar: In stock
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