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THYROID PEROXIDASE

THYROID PEROXIDASE


ArtNr	20-783-73694
Hersteller	GENWAY
Menge	0.2 mg
Kategorie	Oncology Antibodies Cell Biology Cell Metabolism Western Blot ELISA Primary Antibodies By Organ Thyroid Cancer
Typ	Antibody
Applikationen	WB, ELISA
Clon	6H7
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-200826
Similar products	20-783-73694
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Genway ID:	GWB-200826
Specificity:	THYROID PEROXIDASE
Specificity:	THYROID PEROXIDASE
Clone:	6H7
Immunogen:	Human thyroid peroxidase
Specificity Note:	This product is specific for human thyroid peroxidase. Thyroid peroxidase (TPO) is an enzyme expressed in the thyroid gland which is necessary for the production of thyroid hormes such as thyroxine. Congenital hypothyroidism and congenital goiter are both associated with mutations in the TPO gene.
Preparation:	Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution:	Phosphate buffered saline pH 7. 2
Preservative Stabilisers:		0. 09%Sodium Azide (NaN3) Summary: This protein is a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis including congenital hypothyroidism congenital goiter and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined. Summary: This protein is a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis including congenital hypothyroidism congenital goiter and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined. [provided by RefSeq].

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Menge: 0.2 mg

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Lieferung vsl. bis 30.08.2024

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