ArtNr |
20-783-70604 |
Hersteller |
GENWAY
|
Menge |
0.25 mg |
Kategorie |
|
Typ |
Antibody |
Applikationen |
FC, IP |
Clon |
39H5 |
Specific against |
other |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
GWB-9D7E86 |
Similar products |
20-783-70604 |
Lieferbar |
|
Genway ID: |
GWB-9D7E86 |
Specificity: |
CD154NCBI |
Gene ID: |
21947 |
Specificity: |
CD154 |
Clone: |
39H5 |
Immunogen: |
L cell transfected with CD40L |
Specificity Note: |
This product recognises the murine CD154 cell surface antigen a 39kD cell surface glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed by activated CD4+ve T lymphocytes. This product is routinely tested in flow cytometry on mouse CD40L transfected L cells. |
Preparation: |
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant |
Buffer Solution: |
Phosphate buffered saline |
|
Preservative Stabilisers: |
| 0. 09%Sodium AzideSuggested |
Flow Cytometry: |
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested |
Dilution: |
Flow Cytometry - 1/25 - 1/50 |
Function: |
Cytokine that binds to TNFRSF5. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching (By similarity). |
Subunit: |
Homotrimer (By similarity). |
Subcellular Location: |
Cell membrane; Single-pass type II membrane protein (By similarity). |
Subcellular Location: |
CD40 ligand soluble form: Secreted (By similarity). |
Ptm: |
The soluble form derives from the membrane form by proteolytic processing (By similarity). |
Similarity: |
Belongs to the tumor necrosis factor family. 1. Hogg. K. G. et al. (2003) IL-10 regulates early IL-12-mediated immune responses induced by the radiation-attenuated schistosome vaccine. 2. McGregor. C. M. et al. (2004) CD154 is a negative regulator of autoaggressive CD8+ T cells in type 1 diabetes. |
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