Vergleich

CD154

ArtNr 20-783-70604
Hersteller GENWAY
Menge 0.25 mg
Kategorie
Typ Antibody
Applikationen FC, IP
Clon 39H5
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-9D7E86
Similar products 20-783-70604
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Genway ID:
GWB-9D7E86
Specificity:
CD154NCBI
Gene ID:
21947
Specificity:
CD154
Clone:
39H5
Immunogen:
L cell transfected with CD40L
Specificity Note:
This product recognises the murine CD154 cell surface antigen a 39kD cell surface glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed by activated CD4+ve T lymphocytes. This product is routinely tested in flow cytometry on mouse CD40L transfected L cells.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline
Preservative Stabilisers:
0. 09%Sodium AzideSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - 1/25 - 1/50
Function:
Cytokine that binds to TNFRSF5. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching (By similarity).
Subunit:
Homotrimer (By similarity).
Subcellular Location:
Cell membrane; Single-pass type II membrane protein (By similarity).
Subcellular Location:
CD40 ligand soluble form: Secreted (By similarity).
Ptm:
The soluble form derives from the membrane form by proteolytic processing (By similarity).
Similarity:
Belongs to the tumor necrosis factor family. 1. Hogg. K. G. et al. (2003) IL-10 regulates early IL-12-mediated immune responses induced by the radiation-attenuated schistosome vaccine. 2. McGregor. C. M. et al. (2004) CD154 is a negative regulator of autoaggressive CD8+ T cells in type 1 diabetes.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.25 mg
Lieferbar: In stock
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