HSD17B10 Antibody

GWB-94A793

IgG1 Description: Homo sapiens hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10) nuclear gene encoding mitochondrial protein transcript variant 1

WB 1:2000 IHC 1:50 IF 1:100 Flow 1:100 This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids alcohols and steroids. The protein has been implicated in the development of Alzheimer\' s disease and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified but the full-length nature of only two transcript variants has been determined.