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Myeloperoxidase

Myeloperoxidase

ArtNr	20-511-240376
Hersteller	GENWAY
Menge	0.1mg
Kategorie	Oncology Antibodies Cell Biology Cell Status Cell Metabolism Western Blot ELISA Oxidative Stress Primary Antibodies By Organ Heart & Blood Cancer
Typ	Antibody
Applikationen	WB, ELISA
Clon	16G6
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-568C70
Similar products	20-511-240376
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Genway ID:	GWB-568C70
Isotype:	IgG1
Clone:	16G6Host Animal: Mouse. Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Immunogen:	Human myeloperoxidase purified leukocyte mass
Specificity:	Myeloperoxidase
Type of Product:	Monoclonal Antibodies to Cardiac Markers
Concentration:	3. 0mg/ml (Sigma protein assay kit)Preservatives: NaN3
Buffer:	PBS pH 7. 4Applications Notes : Suitable for use in ELISA and Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Warning:	This product contains sodium azide which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0. 1â ??1. 0%. When disposing of this reagent through lead or copper plumbing flush with copious volumes of water to prevent azide build-up in drains. MAb to Myeloperoxidase. Monoclonal Antibody to Human Myeloperoxidase
Function:	Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN MPO catalyzes the production of hypohalous acids primarily hypochlorous acid in physiologic situations and other toxic intermediates that greatly enhance PMN microbicidal activity.
Catalytic Activity:	Donor + H2O2 = oxidized donor + 2 H2O.
Catalytic Activity:	Cl- + H2O2 = HOCl + 2 H2O. Cofactor: Binds 1 calcium ion per heterodimer. Cofactor: Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer.
Subunit:	Tetramer of two light chains and two heavy chains.
Subcellular Location:	Lysosome.
Disease:	Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
Similarity:	Belongs to the peroxidase family. XPO subfamily.

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Menge: 0.1mg

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