L1 [MAC387]

GWB-56237D

IgG1

Human

Human spleen

1. 0 mg/ml

Buffer contains 0. 09% sodium azide

Use at a dilution of 1:50 - 1:100. For IHC-Fr and IHC-P: Use at a dilution of 1:100 - 1:200. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. ** This product requires protein digestion pre-treatment e. g. trypsin 0. 1% for 10 minutes or antigen retrieval using heat treatment prior to staining of paraffin sections. Myeloma: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line The L1 protein is a member of the S100 family of proteins. These proteins are limited to the cytoplasm and/or nucleus of a wide variety of cells. They regulate more than a few cellular processes including differentiation and cell cycle progression. Cystic fibrosis is linked to altered expression of this protein.

Interacts with CEACAM3 in a calcium-dependent manner.

Belongs to the S-100 family.