GluR3

GWB-A26CAF

A synthetic peptide corresponding to residues in the human Glutamate receptor type 3 was used as an immunogen.

WB: 1:1 000-5 000IHC: 1:50-100ICC: 1:50-100IP: 1:50. Glutamate receptor type 3 (GluR3) is one of the four subunits of a-amino-5-hydroxy-3-methyl-4-isoxazole propionic acid (AMPA) receptor. AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS). AMPA receptors are composed of four types of subunits designated as GluR1 GluR2 GluR3 and GluR4 (alternatively called GluRA-D) which combine to form tetramers. The complex composed of GluR2 and GluR3 is one of the two predominant forms in the adult hippocampus. All four GluRs interact with specific cytoplasmic protein through their C-terminal tails. Although in contrast to GluR1 and GluR4 GluR3 and GluR2 have a short C-terminal tail. 1. Han J. ; Lee J. -D. ; Jiang Y. ; Li Z. ; Feng L. ; Ulevitch R. J. : J. Biol. Chem. 271: 2886-2891 1996. 2. Seger R. ; Krebs E. G. : FASEB J. 9: 726-735 1995. 3. Bernd Stein Helen Brady Maria X. Yang David B. Young Miguel S. Barbosa Volume 271 Number 19 Issue of May 10 1996 pp. 11427-114334. Fujishiro et al. J. Biol. Chem. Vol. 276 Issue 23 19800-19806 20015. Manufactured under U. S. Patents No. 5 675 063 and 7 429 487