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Rabbit A\&#039, Opioid Receptor mu

Rabbit A\&#039, Opioid Receptor mu

ArtNr	18-511-244144
Hersteller	GENWAY
Menge	0,1 ml
Kategorie	Antibodies Primary Antibodies
Typ	Antibody
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-48E5DA
Similar products	18-511-244144
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Genway ID:	GWB-48E5DA
Host Animal:	Rabbit
Immunogen:	Peptide analogue of the carboxyl terminal of the mu opioid receptor covalently attached to a carrier protein.
Specificity:	Opioid Receptor mu (carboxyl terminal) (a. a. 391-398)
Specificity:	Specific for Mu Opioid Receptor (carboxyl terminal) (a. a. 391-398). This antisera has been characterized by Western blotting ELISA and cell staining techniques. Cross-re
Activity:	Mu Opioid Receptor (391-398) 100% Mu Opioid Receptor 50% Delta Opioid Receptor (360-371) 0% Delta Opioid Receptor 0% Kappa Opioid Receptor (346-380) 0% Kappa Opioid Receptor 0%
Type of Product:	Polyclonal Antibodies for Neuroscience
Concentration:	Not determined.
Buffer:	Not applicable. Applications Notes : Suitable for immunocytochemical and western immunoblotting detection of the receptor. Has been found to stain specific cells in various regions of PLP fixed rat brain sections known to express the mu opioid receptor using ABC techniques at a dilution of 1:2 000. Western immunoblots using whole rat brain homogenate have been successful at a dilution of 1:500. Each laboratory should determine an optimum working titer for use in its particular application. Rabbit A\' Opioid Receptor mu. Rabbit Antibody to Opioid Receptor Mu (carboxyl terminal) (amino acids 391-398)
Function:	Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin.
Subcellular Location:	Cell membrane; Multi-pass membrane protein.
Polymorphism:	Variant Asp-40 does not show altered binding affinities for most opioid peptides and alkaloids tested but it binds beta-endorphin an endogenous opioid that activates the mu opioid receptor approximately 3 times more tightly than the most common allelic form.
Similarity:	Belongs to the G-protein coupled receptor 1 family [view classification].

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