Vergleich

ADAM8

ArtNr 18-272-195428
Hersteller GENWAY
Menge 0,05 mg
Typ Antibody
Applikationen WB
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-5FBEF6
Similar products 18-272-195428
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Genway ID:
GWB-5FBEF6
Isotype:
IgG
Immunogen:
Synthetic peptide (Human) corresponding to the amino terminal end of the catalytic domain.
Antigen Species:
Human
Specificity:
Does not react with other ADAMs.
Target:
ADAM8
Localization:
Cell Membrane
Concentration:
1 mg/ml Storage
Preservative:
0. 05% Sodium Azide; Constituents: 50% Glycerol PBS
Application Note:
WB: Use at a dilution of 1/1000. Detects bands of approximately 75 kDa and 60 kDa (in reduced sample). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Cellular
Localization:
Cell Membrane Members of ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. The extracellular region of ADAM8 shows significant amino acid sequence homology to hemorrhagic snake venom proteins including the metalloprotease and disintegrin domains. The expression of ADAM8 is upregulated by retinoic acid and vitamin D3. ADAM8 is involved in protein processing at the cell surface and is also thought to act as a leukocyte differentiation marker.
Function:
Possible involvement in extravasation of leukocytes. Cofactor: Binds 1 zinc ion per subunit (Probable).
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed on neutrophils and monocytes.
Similarity:
Contains 1 disintegrin domain.
Similarity:
Contains 1 EGF-like domain.
Similarity:
Contains 1 peptidase M12B domain [view classification].

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0,05 mg
Lieferbar: In stock
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