SOX17

GWB-C02DA2

Peptide with sequence EALPCRDGTDP from the internal region of the Notes: Peptide ELISA: antibody detection limit dilution 1:32 000. Western Blot: Preliminary experiments gave an approx 20kDa band in Rat Brain and Rat Spinal Cord lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 44. 6kDa according to Mouse NP_035571. 1 and of 44. 1kDa according to Human NP_071899. 1. The 20kDa band was successfully blocked by incubation with the immunizing peptide. Summary: This protein is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq]. [1] Bilguvar K. Yasuno K. Niemela M. Ruigrok Y. M. von Und Zu Fraunberg M. van Duijn C. M. van den Berg L. H. Mane S. et al. Susceptibility loci for intracranial aneurysm in European and Japanese populations[2] Semb H. et al. Expandable endodermal progenitors: new tools to explore endoderm and its derivatives[3] Patterson E. S. Addis R. C. Shamblott M. J. and Gearhart J. D. et al. SOX17 directly activates Zfp202 transcription during in vitro endoderm differentiation[4] Zhang W. Glockner S. C. Guo M. Machida E. O. Wang D. H. Easwaran H. Van Neste L. Herman J. G. Schuebel K. E. et al. Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer[5] Ferrell R. E. Kimak M. A. Lawrence E. C. and Finegold D. N. et al. Candidate gene analysis in primary lymphedema