PJA1

GWB-3622DE

Peptide with sequence GQESSKPVWPNPT-C from the N Terminus of the Notes: Peptide ELISA: antibody detection limit dilution > 1:32 000. Western Blot: Approx. 25-30kDa band observed in human brain and human testis lysates at 0. 5ug of primary. Please note that the band we observe is different from the predicted size of approx. 74kDa and 52kDa according to AF262024 and NP_071763 respectively. [1] Ross M. T. Grafham D. V. Coffey A. J. Scherer S. McLay K. Muzny D. Platzer M. Howell G. R. Burrows C. Bird C. P. et al. The DNA sequence of the human X chromosome[2] Sasaki A. Masuda Y. Iwai K. Ikeda K. and Watanabe K. et al. A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein Dlxin-1[3] Yu P. Chen Y. Tagle D. A. and Cai T. et al. PJA1 encoding a RING-H2 finger ubiquitin ligase is a novel human X chromosome gene abundantly expressed in brain[4] Fang S. Jensen J. P. Ludwig R. L. Vousden K. H. and Weissman A. M. et al. Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53[5] Mishra L. Tully R. E. Monga S. P. Yu P. Cai T. Makalowski W. Mezey E. Pavan W. J. and Mishra B. Praja1 a novel gene encoding a RING-H2 motif in mouse development