CTBP1 (C-terminal binding protein 1)

GWB-4361D7

1:62500

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. Summary: This protein is a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene CTBP2 can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. Spyer. M. . et al. . (2006) Cell Cycle 5 (5). 530-537.