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GRHL3 (grainyhead-like 3 (Drosophila))

ArtNr 18-003-43369
Hersteller GENWAY
Menge 0.1 mg
Kategorie
Typ Antibody
Applikationen WB, IHC
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-5D37EB
Similar products 18-003-43369
Lieferbar
Genway ID:
GWB-5D37EB
Antigen Specificity:
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human GRHL3. Western Blot: Suggested dilution at 2. 5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50. 000 - 100. 000 as second antibody.
ELISA Titre:
1:1562500
Note:
Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.
Description:
GRHL3 is a member of the grainyhead family of transcription factors. GRHL3 interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM) and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM) and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described but their biological nature has not been determined. This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM) and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described but their biological nature has not been determined. GRHL3 is a member of the grainyhead family of transcription factors. GRHL3 interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM) and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM) and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described but their biological nature has not been determined. This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM) and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described but their biological nature has not been determined.
Function:
May function as a transcription factor.
Subunit:
Homodimer also forms heterodimers with GRHL1 and GRHL2.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in brain colon pancreas placenta and kidney. Isoform 1 is expressed in lung and tonsil. Isoform 2 is prostate-specific.
Similarity:
Belongs to the grh/CP2 family. Grainyhead subfamily. Summary: This protein is a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM) and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described but their biological nature has not been determined. Ting. S. B. . Biochem. J. 370 (PT 3). 953-962 (2003).

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Menge: 0.1 mg
Lieferbar: In stock
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Lieferung vsl. bis 27.09.2024 

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