RABBIT ANTI MOUSE CYTOKERATIN 19

CYTOKERATIN 19

Phosphate buffered saline

A synthetic peptide corresponding to amino acids 21-40 of mouse cytokeratin 19 - conjugated to KLH

Involved in the organization of myofibers. Together with KRT8 helps to link the contractile apparatus to dystrophin at the costameres of striated muscle By similarity. Subunit structureHeterotetramer of two type I and two type II keratins. Interacts with PNN and the actin-binding domain of DMD By similarity. Developmental stageExpressed throughout embryonic development with highest levels at 8. 5 dpc. Expression decreases by 11. 5 dpc and increases again by 17. 5 dpc. Ref. 2

There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa). Sequence similaritiesBelongs to the intermediate filament family. 1. Krop I. et al. (1996) Self-renewal of B-1 lymphocytes is dependent on CD19 Eur. J. Immunol. 26: 238. 2. Vernooy J. et al. (2002) Long-term intratracheal lipopolysaccharide exposure in mice results in chronic lung inflammation and persistent pathology. Am. J. Respir. Cell. Mol. Biol. 26: 152-159. [1] \" Structure and domain organization of the CD19 antigen of human mouse and guinea pig B lymphocytes. Conservation of the extensive cytoplasmic domain. \" Zhou L. J. Ord D. C. Hughes A. L. Tedder T. F. J. Immunol. 147:1424-1432(1991) [PubMed: 1714482] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: BALB/c. Tissue: Spleen. [2] \" Structure of the genes encoding the CD19 antigen of human and mouse B lymphocytes. \" Zhou L. J. Ord D. C. Omori S. A. Tedder T. F. Immunogenetics 35:102-111(1992) [PubMed: 1370948] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Tissue: Spleen. [3] \" Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily. \" Tedder T. F. Isaacs C. M. J. Immunol. 143:712-717(1989) [PubMed: 2472450] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 302-547. Strain: BALB/c. Tissue: Spleen. [4] \" The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP. \" Kozmik Z. Wang S. Doerfler P. Adams B. Busslinger M. Mol. Cell. Biol. 12:2662-2672(1992) [PubMed: 1375324] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-26. [5] \" Phosphoproteome analysis of mouse liver using immobilized metal affinity purification and linear ion trap mass spectrometry. \" Jin W. -H. Dai J. Zhou H. Xia Q. -C. Zou H. -F. Zeng R. Rapid Commun. Mass Spectrom. 18:2169-2176(2004) [PubMed: 15378723] [Abstract]Cited for: PHOSPHORYLATION AT SER-225.