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Atriopeptin III, rat

Atriopeptin III, rat

ArtNr	RP11203-0.5
Hersteller	GenScript
Menge	0.5 mg
Kategorie	Peptides & Proteins Cardiovascular Research Heart Failure Myocardial Infarction Hypertension Peptides
Typ	Peptides
Specific against	Rat (Rattus norvegicus)
Purity	> 95%
Sequence	SSCFGGRIDRIGAQSGLGCNSFRY ; {SER}{SER}{CYS}{PHE}{GLY}{GLY}{ARG}{ILE}{ASP}{ARG}{ILE}{GLY}{ALA}{GLN}{SER}{GLY}{LEU}{GLY}{CYS}{ASN}{SER}{PHE}{ARG}{TYR}
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP11203-Atriopeptin_III_rat, Atriopeptin is a 28 amino acid peptide synthesized primarily in cardiac atria. Atriopeptin acts in opposition to angiotensin II in regulating renal, hemodynamic, and endocrine function. Atriopeptin is released in response to the increased pressure and mechanical stretch of the right atrium due to blood volume overload. Atriopeptin then acts at the nephron to increase salt and water excretion, lowering blood volume and blood pressure. The effects of atriopeptin III (AP III) on in vitro prepared afferent (AA) and efferent arterioles (EA) from rat kidneys were tested in a system in which lumen diameter could be measured. AP III (10(-13)-10(-7) M) had no effect on lumen diameter of AA that were not preconstricted. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Store at -20C </td></tr>
Similar products	Atriopeptin
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Country of Origin	USA
Storage Conditions	Store at -20C
Description	Atriopeptin is a 28 amino acid peptide synthesized primarily in cardiac atria. Atriopeptin acts in opposition to angiotensin II in regulating renal, hemodynamic, and endocrine function. Atriopeptin is released in response to the increased pressure and mechanical stretch of the right atrium due to blood volume overload. Atriopeptin then acts at the nephron to increase salt and water excretion, lowering blood volume and blood pressure. The effects of atriopeptin III (AP III) on in vitro prepared afferent (AA) and efferent arterioles (EA) from rat kidneys were tested in a system in which lumen diameter could be measured. AP III (10(-13)-10(-7) M) had no effect on lumen diameter of AA that were not preconstricted.
Chemical Bridge	Disulfide bridge: Cys3-Cys19

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Menge: 0.5 mg

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