ArtNr |
A01426-40 |
Hersteller |
GenScript
|
Menge |
40ug |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, other |
Specific against |
other |
Host |
Rabbit |
Isotype |
IgG |
Konjugat/Tag |
Unconjugated |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
A01426-Caspr2_Antibody_pAb_Rabbit,Contacting-associated protein 2 antibody, |
Similar products |
Caspr2 |
Lieferbar |
|
Specificity |
GenScript Rabbit Anti-Caspr2 Polyclonal Antibody detects endogenous levels of mouse and rat Caspr2. It is predicted to react with human Caspr2 according to sequence homology. Positive Control: mouse brain and rat brain. |
Isotype Information |
Rabbit IgG |
Specificity |
GenScript Rabbit Anti-Caspr2 Polyclonal Antibody detects endogenous levels of mouse and rat Caspr2. It is predicted to react with human Caspr2 according to sequence homology. Positive Control: mouse brain and rat brain. |
Antigen Species |
Human |
Concentration |
0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
Description |
Contacting-associated protein 2 (Caspr2) is a member of the neurexin superfamily that mediates nervous system cell-cell interactions. The C-terminal region of Caspr2 participates in the association with Kv1.1, Kv1.2 and their Kv-beta-2 subunit. Expression of Caspr2 is regulated directly by transcription factor FOXP2. Disruption or decreased expression of Caspr2 probably leads to a disturbed distribution of potassium channels in the nervous system. Mutations in the Caspr2 gene have been linked to many diseases such as focal epilepsy, autism spectrum disorder and cortical dysplasia-focal epilepsy syndrome (CDFES). GenScript, Rabbit Anti-Caspr2 Polyclonal Antibody, is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human Caspr2 (Swiss Prot: Q9UHC6). |
Immunogen |
KLH-coupled synthetic peptide from C-terminal of human Caspr2 (Swiss Prot: Q9UHC6) |
Purification Method |
Immunoaffinity chromatography |
Reconstitution |
Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml. |
Species Reactivity |
Mouse and rat. This product has not been tested for other species yet. |
Storage |
The antibody is stable in lyophilized form if stored at -20C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8C. For long term storage, aliquot and store at -20C or below. Avoid repeated freezing and thawing cycles. |
Product Origin |
USA |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.