ArtNr |
E18-0046-2 |
Hersteller |
Enogene
|
Menge |
100ug/100ul |
Kategorie |
|
Typ |
Antibody |
Applikationen |
Western Blot, Immunohistochemistry |
Specific against |
Human, Mouse, Rat |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Beta-PAK, bPAK, CDKN1A, hPAK3, MRX30, MRX47, Oligophrenin-3, OPHN3, p21 (CDKN1A)-activated kinase 3, p21 protein (Cdc42/Rac)-activated kinase 3, p21-activated kinase 3, PAK-3, PAK3, PAK3beta, Serine/threonine-protein kinase PAK 3 |
Lieferbar |
|
Background |
PAK3 a protein kinase of the STE20 family that regulates synapse formation and plasticity in the hippocampus. May be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Forms an activated complex with GTP-bound P21, CDC2 and RAC1 proteins. Missense and truncation mutations linked to nonsyndromic mental retardation type 30 (MRX30). Two alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB. |
Swiss-Prot No. |
O75914 |
Form of Antibody |
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 C.Stable for 12 months from date of receipt |
Immunogen |
A synthesized peptide derived from human PAK3 around the phosphorylation site of Sersine 154 |
Purification |
Immunogen affinity purified |
Specificity/Sensitivity |
Phospho-PAK3(Ser154) Antibody detects endogenous levels of PAK3 only when phosphorylated at Sersine 154 |
Applications information |
WB 1:500-1:2000 IHC 1:50-1:200 |
Molecular Weight |
72kDa |
Storage/Stability |
Store at -20C/1 year |
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